BDBM649878 US20240043403, Example 115

SMILES CN(C)[C@@H]1CCN2CCN(C[C@@H]12)c1c(NC(=O)c2coc(n2)-c2ccnnc2)ccc(Oc2ccccc2)c1C(F)(F)F

InChI Key InChIKey=QEMKLTIPLROOGG-RPWUZVMVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649878   

TargetDiacylglycerol kinase delta(Human)
Astellas Pharma

US Patent
LigandPNGBDBM649878(US20240043403, Example 115)
Affinity DataIC50:  7.90nMAssay Description:To a 384-well plate (Greiner Bio-One Co., Ltd.), 3 μL of a DGK ξ enzyme dissolved in an assay buffer (40 mM Tris-HCl pH 7.5, 10 mM MgCl2, 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent