BDBM65518 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)::668467-91-2::LDN-57444

SMILES CC(=O)ON=C1C(=O)N(Cc2cc(Cl)ccc2Cl)c2ccc(Cl)cc12

InChI Key InChIKey=OPQRFPHLZZPCCH-PGMHBOJBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 65518   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
University of Delaware

LigandPNGBDBM65518(5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...)
Affinity DataIC50:  2.50E+3nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L5(Homo sapiens (Human))
University of Delaware

LigandPNGBDBM65518(5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...)
Affinity DataIC50:  1.62E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
University of Delaware

LigandPNGBDBM65518(5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...)
Affinity DataIC50:  1.41E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed