BDBM68251 Microlactone, 16b

SMILES CC1C[C@H]2O[C@@H]2CCCCC(=O)Cc2c(Cl)c(O)cc(O)c2C(=O)O1

InChI Key InChIKey=ZGZOBNGYHLFQFW-ANWCPOMBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 68251   

TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University of Nottingham

LigandPNGBDBM68251(Microlactone, 16b)
Affinity DataIC50:  1.90E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University of Nottingham

LigandPNGBDBM68251(Microlactone, 16b)
Affinity DataIC50:  250nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University of Nottingham

LigandPNGBDBM68251(Microlactone, 16b)
Affinity DataIC50:  310nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed