BDBM70809 US9546164, 2::US9694002, 2
SMILES Fc1cc(O[C@H]2CCCN(Cc3ccccc3)C2)c(cc1C(=O)NS(=O)(=O)N1CCC1)C1CC1
InChI Key InChIKey=NVDJRUZWJVKEIQ-FQEVSTJZSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 70809
TargetSodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 4.12E+3nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMpH: 7.2Assay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 4.12E+3nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+3nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair