BDBM7497 1-Azakenpaullone::14-bromo-3,8,18-triazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one::US11759530, Compound Table1.11

SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4cccnc-34)c2c1

InChI Key InChIKey=NTSBZVCEIVPKBJ-UHFFFAOYSA-N

Data  13 IC50  1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7497   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Rockefeller University

Curated by ChEMBL

LigandBDBM7497(1-Azakenpaullone | 14-bromo-3,8,18-triazatetracycl...)Copy SMILESCopy InChI

Affinity DataIC50:  18nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
The Rockefeller University

Curated by ChEMBL

LigandBDBM7497(1-Azakenpaullone | 14-bromo-3,8,18-triazatetracycl...)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK1/cyclinBMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI