BDBM7960 1H-1,3-benzodiazol-2-amine::2-Aminobenzimidazole::CHEMBL305513::CRA Fragment 9::Imidazole C-2 deriv. 3::JMC524454 Compound 5::US11584714, Compound 46

SMILES Nc1nc2ccccc2[nH]1

InChI Key InChIKey=JWYUFVNJZUSCSM-UHFFFAOYSA-N

Data  5 KI  8 IC50  1 Kd

PDB links: 24 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7960   

TargetMembrane primary amine oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Rattus norvegicus (Rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed