BDBM8033 (2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-(3-phenylphenyl)ethyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-3-methyl-2-(pyridin-2-ylformamido)butanamide::(2S,5S,6R)-3-Aza-5-hydroxy-7-phenyl-2-(m-phenylbenzyl)-6-[(picolyl-L-valinyl)amino]heptanoyl Amide::hydroxyethylamine-based inhibitor 17a

SMILES CC(C)[C@H](NC(=O)c1ccccn1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN[C@@H](Cc1cccc(c1)-c1ccccc1)C(N)=O

InChI Key InChIKey=HUPMEFWUWBYIQC-YRCZKMHPSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8033   

TargetPlasmepsin II(Plasmodium falciparum)
Uppsala University

LigandPNGBDBM8033((2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-(3-phenylph...)
Affinity DataKi:  579nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
Uppsala University

LigandPNGBDBM8033((2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-(3-phenylph...)
Affinity DataKi:  1.00E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Uppsala University

LigandPNGBDBM8033((2S)-N-[(2S,3S)-4-{[(1S)-1-carbamoyl-2-(3-phenylph...)
Affinity DataKi:  1.60E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed