BDBM81327 Tetrahydroquinoxalin analog, J

SMILES O=c1[nH]c2ccc(Oc3ccc4[nH]c(=O)c(=O)[nH]c4c3)cc2[nH]c1=O

InChI Key InChIKey=GYFIYMNWPNHJED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 81327   

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Brandeis University

LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50:  5.90E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Brandeis University

LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed