BDBM81328 methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylate, Compound E::methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylate, E

SMILES COC(=O)c1c(C)c(=O)[nH]c2ccccc12

InChI Key InChIKey=ZNCUPPCJISULRA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 81328   

TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50: >2.50E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50: >2.50E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50:  1.60E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Streptococcus pyogenes)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50:  1.50E+4nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Helicobacter pylori (strain G27))
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50:  1.50E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Borrelia burgdorferi)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50:  900nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50:  1.60E+3nMpH: 8.0 T: 2°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed