BDBM81396 GMX1778

SMILES Clc1ccc(OCCCCCCNC(NC#N)=Nc2ccncc2)cc1

InChI Key InChIKey=BOIPLTNGIAPDBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 81396   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

LigandPNGBDBM81396(GMX1778)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The reaction was carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well plates. NAMPT protein was added to 1 B...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

LigandPNGBDBM81396(GMX1778)
Affinity DataIC50:  0.0700nMAssay Description:In vitro inhibition assay using human nampt, NMN adenylytransferase (nmant1)and UDP-glucose dehdryogenase (ugdh) genes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed