BDBM81462 (R)-Trihexyphenidyl::(S)-Trihexyphenidyl::Benzhexol::CAS_58947-95-8::NSC_5572::TRIHEXYPHENIDYL HYDROCHLORIDE::Trihexyphenidyl

SMILES OC(CCN1CCCCC1)(C1CCCCC1)c1ccccc1

InChI Key InChIKey=HWHLPVGTWGOCJO-UHFFFAOYSA-N

Data  22 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 81462   

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  0.370nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  0.830nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  2.45nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  5.01nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  7.08nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  123nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  269nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  490nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  676nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81462((R)-Trihexyphenidyl | (S)-Trihexyphenidyl | Benzhe...)
Affinity DataKi:  1.29E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank