BDBM8147 3-(2-{[3-(Trifluoromethyl)phenyl]amino}-4-pyrimidin-yl)pyrazolo[1,5-b]pyridazin-6-ol::5-(2-{[3-(trifluoromethyl)phenyl]amino}pyrimidin-4-yl)pyrazolo[1,5-a]pyridazin-2-ol::pyrazolo[1,5-b]pyridazine deriv. 38

SMILES FC(F)(F)c1cccc(Nc2nccc(n2)-c2cnn3[nH]c(=O)ccc23)c1

InChI Key InChIKey=FEQLPEIKSCUTRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8147   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8147(3-(2-{[3-(Trifluoromethyl)phenyl]amino}-4-pyrimidi...)
Affinity DataIC50:  16nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8147(3-(2-{[3-(Trifluoromethyl)phenyl]amino}-4-pyrimidi...)
Affinity DataIC50:  8nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed