BDBM81554 MgrA inhibitor, 3
SMILES Cc1ccc(C)n1[C@@H](CC(O)=O)Cc1c[nH]c2ccccc12
InChI Key InChIKey=NXFPHEKDOYHPIB-OAHLLOKOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 81554
TargetHTH-type transcriptional regulator MgrA(Staphylococcus aureus)
University Of Nottingham
Curated by ChEMBL
University Of Nottingham
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Staphylococcus aureus Newman His6-tagged MgrA expressed in Escherichia coli BL21(DE3) using 5'-6-F-TAAACAACAAGTTGTCCAAA-3' as substrate...More data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator MgrA(Staphylococcus aureus)
University Of Nottingham
Curated by ChEMBL
University Of Nottingham
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence anisotropy (FA)-based biochemical assay that monitors MgrA-DNA binding. To determine the binding affinity of MgrA to the labeled DNA,...More data for this Ligand-Target Pair