BDBM82018 CAS_790::CHEMBL1427::Hypoxanthine::NSC_790
SMILES O=c1[nH]cnc2nc[nH]c12
InChI Key InChIKey=UYLWKSJTHLRFBX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 82018
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
Affinity DataKd: 680nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 82018
ITC DataΔG°: -7.40kcal/mole logk: 2.70E+5
pH: 7.4 T: 25.00°C
pH: 7.4 T: 25.00°C
ITC DataΔH°: -30.6kcal/mole
pH: 7.4 T: 27.00°C
pH: 7.4 T: 27.00°C