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Target
Purine nucleoside phosphorylase
Ligand
BDBM82018
Substrate
n/a
Meas. Tech.
ChEMBL_854810 (CHEMBL2162055)
Kd
680±n/a nM
Citation
 Wielgus-Kutrowska, B; Breer, K; Hashimoto, M; Hikishima, S; Yokomatsu, T; Narczyk, M; Dyzma, A; Girstun, A; Staron, K; Bzowska, A Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state. Bioorg Med Chem 20:6758-69 (2012) [PubMed]  Article 
Target
Name:
Purine nucleoside phosphorylase
Synonyms:
Inosine phosphorylase | NP | PNP | PNPH_BOVIN | Purine Nucleoside Phosphorylase (PNP) | Purine nucleoside phosphorylase
Type:
Enzyme
Mol. Mass.:
32035.18
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
289
Sequence:
MANGYTYEDYQDTAKWLLSHTEQRPQVAVICGSGLGGLVNKLTQAQTFDYSEIPNFPESTVPGHAGRLVFGILNGRACVMMQGRFHMYEGYPFWKVTFPVRVFRLLGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFSGENPLRGPNEERFGVRFPAMSDAYDRDMRQKAHSTWKQMGEQRELQEGTYVMLGGPNFETVAECRLLRNLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESQGKANHEEVLEAGKQAAQKLEQFVSLLMASIPVSGHTG
  
Inhibitor
Name:
BDBM82018
Synonyms:
CAS_790 | CHEMBL1427 | Hypoxanthine | NSC_790
Type:
Small organic molecule
Emp. Form.:
C5H4N4O
Mol. Mass.:
136.1115
SMILES:
O=c1[nH]cnc2nc[nH]c12
Structure:
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