BDBM82124 adenosine-derived inhibitor (Grp78), 1
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O
InChI Key InChIKey=XTWYTFMLZFPYCI-KQYNXXCUSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 82124
Affinity DataKi: 110nM ΔG°: -9.49kcal/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKd: 500nMpH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
Affinity DataKd: 2.17E+3nM Kon: 0.00500M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 82124
ITC Data−TΔS°: -6.09kcal/mole ΔH°: -1.29kcal/mole logk: 3.83E+3
pH: 7.4 T: 25.00°C
pH: 7.4 T: 25.00°C