BDBM82127 (2R,3R,4S,5R)-2-(6-Amino-8-methylaminopurin-9-yl)-5- (pyridin-3-ylmethoxymethyl)tetrahydrofuran-3,4-diol::adenosine-derived inhibitor (Grp78), 6
SMILES CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COCc2cccnc2)[C@@H](O)[C@H]1O
InChI Key InChIKey=YFNVDWQSHZOXMH-XNIJJKJLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 82127
Affinity DataKi: 450nM ΔG°: -8.65kcal/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
Affinity DataKd: 2.71E+3nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair