BDBM82128 2-[(2R,3S,4R,5R)-5-(6-Amino-8-methylaminopurin-9-yl)- 3,4-dihydroxytetrahydrofuran-2-ylmethoxy]acetamide::adenosine-derived inhibitor (Grp78), 7

SMILES CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COCC(N)=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=YTEPWBADDXGTBX-JJNLEZRASA-N

Data  1 KI  1 Kd  1 Koff

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 82128   

TargetHeat shock 70 kDa protein 1A(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM82128(2-[(2R,3S,4R,5R)-5-(6-Amino-8-methylaminopurin-9-y...)
Affinity DataKi:  1.85E+3nM ΔG°:  -7.82kcal/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum chaperone BiP(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM82128(2-[(2R,3S,4R,5R)-5-(6-Amino-8-methylaminopurin-9-y...)
Affinity DataKd:  1.24E+4nM Kon: >1M-1s-1pH: 7.4 T: 2°CAssay Description:SPR measurements wereperformed on BIAcore T100 instrument (BIAcore GE Healthcare), at25 C on series S NTA chips (certified) according to provider'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed