BDBM8346 6-aryl-pyrazolo[3,4-b]pyridine analogue 10::N-[6-(2-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]cyclopropanecarboxamide

SMILES Oc1ccccc1-c1ccc2c(NC(=O)C3CC3)n[nH]c2n1

InChI Key InChIKey=RHNUSTPOMUKRCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8346   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8346(6-aryl-pyrazolo[3,4-b]pyridine analogue 10 | N-[6-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8346(6-aryl-pyrazolo[3,4-b]pyridine analogue 10 | N-[6-...)
Affinity DataIC50:  36nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed