BDBM8360 4-(4-ethylpiperazin-1-yl)-N-[6-(3-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]butanamide::6-aryl-pyrazolo[3,4-b]pyridine analogue 24

SMILES CCN1CCN(CCCC(=O)Nc2n[nH]c3nc(ccc23)-c2cccc(O)c2)CC1

InChI Key InChIKey=OVTRGRMOTBJXKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8360   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8360(4-(4-ethylpiperazin-1-yl)-N-[6-(3-hydroxyphenyl)-1...)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8360(4-(4-ethylpiperazin-1-yl)-N-[6-(3-hydroxyphenyl)-1...)
Affinity DataIC50:  21nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed