BDBM84461 HIV-1 PR Inhibitor, compound 8

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)n1cc(CNC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)nn1

InChI Key InChIKey=XWYIBXKLXLXYMK-SZAHLOSFSA-N

Data  5 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 84461   

TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  4nM IC50:  13nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  4nMAssay Description:Binding affinity to HIV1 protease assessed as inhibition constantMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  9.70nM IC50:  17nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  13nM IC50:  24nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
The Scripps Research Institute

LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataKi:  30nM IC50:  52nMAssay Description:The inhibition activity against HIV-1 PR and three mutants (G48V, V82F, V82A)were done in 96 well microtiter plate and were assayed. Wells that show...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM84461(HIV-1 PR Inhibitor, compound 8)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant HIV1 ProteaseMore data for this Ligand-Target Pair