BDBM84532 Alsterpaullone derivative, 6

SMILES COC(=O)CCc1ccc2NC(=O)Cc3c([nH]c4ccc(cc34)[N+]([O-])=O)-c2c1

InChI Key InChIKey=FIKVDYWIFLBJSG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 84532   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84532(Alsterpaullone derivative, 6)
Affinity DataIC50:  34nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84532(Alsterpaullone derivative, 6)
Affinity DataIC50:  250nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84532(Alsterpaullone derivative, 6)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed