BDBM84981 Luteolin-7,3',4'-trimethylether

SMILES COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(OC)c(OC)c1

InChI Key InChIKey=HIXDQWDOVZUNNA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 84981   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard Karls University of Tuebingen

LigandPNGBDBM84981(Luteolin-7,3',4'-trimethylether)
Affinity DataIC50:  3.32E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM84981(Luteolin-7,3',4'-trimethylether)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM84981(Luteolin-7,3',4'-trimethylether)
Affinity DataIC50:  2.17E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed