BDBM85276 HEA derivative, 7c::MurC/D/E/F inhibitor (compound 68)
SMILES OP(O)(=O)OC(CNS(=O)(=O)c1ccc(cc1)C(F)(F)F)CN1CCOCC1
InChI Key InChIKey=UJEZOYULDAIFDY-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 85276
Affinity DataIC50: 2.00E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana
University of Ljubljana
Affinity DataIC50: 5.70E+4nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University of Ljubljana
University of Ljubljana
Affinity DataIC50: 2.40E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University of Ljubljana
University of Ljubljana
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University of Ljubljana
University of Ljubljana
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University of Ljubljana
University of Ljubljana