BDBM85279 HEA derivative, 7f

SMILES CCc1ccc(cc1)S(=O)(=O)NCC(CN1CCOCC1)OP(O)(O)=O

InChI Key InChIKey=XFGULWIEUBKFRY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85279   

TargetUDP-N-acetylmuramate--L-alanine ligase(Escherichia coli)
University Of Ljubljana

LigandPNGBDBM85279(HEA derivative, 7f)
Affinity DataIC50:  7.60E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Escherichia coli)
University Of Ljubljana

LigandPNGBDBM85279(HEA derivative, 7f)
Affinity DataIC50:  3.60E+5nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase(Staphylococcus aureus)
University Of Ljubljana

LigandPNGBDBM85279(HEA derivative, 7f)
Affinity DataIC50:  6.10E+4nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed