BDBM85515 Ampyrone::CAS_83-07-8::EN300-17058::NSC_2151::US11643395, Compound 9

SMILES Cc1c(N)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=RLFWWDJHLFCNIJ-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 85515   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

Curated by ChEMBL
LigandPNGBDBM85515(Ampyrone | CAS_83-07-8 | EN300-17058 | NSC_2151 | ...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver estera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM85515(Ampyrone | CAS_83-07-8 | EN300-17058 | NSC_2151 | ...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver est...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed