BDBM88379 US9695131, 16::US9695131, 17::US9695131, 18

SMILES Cn1c2ccc(cc2n(C)c1=O)-n1cc(-c2nnn[nH]2)c(=O)n(C2CCc3c2cccc3Cl)c1=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 88379   

Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM88379(US9695131, 16 | US9695131, 17 | US9695131, 18)
Affinity DataIC50:  4.60nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM88379(US9695131, 16 | US9695131, 17 | US9695131, 18)
Affinity DataIC50:  42nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM88379(US9695131, 16 | US9695131, 17 | US9695131, 18)
Affinity DataIC50:  2.80nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In DepthDetails US Patent