BDBM8960 (+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one::2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one::Aricept::Aricept odt::CHEMBL1678::CHEMBL2337271::CHEMBL502::DONEPEZIL HYDROCHLORIDE::Donepezil::Donepzil::E2020::US8999994, Donepezil::US9346818, DPH::US9586925, Donepezil::US9663465, Donepezil
SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
InChI Key InChIKey=ADEBPBSSDYVVLD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 8960
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology
Curated by ChEMBL
The Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology
Curated by ChEMBL
The Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology
Curated by ChEMBL
The Hong Kong University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.72E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair