BDBM9068 2-[7-(1,2,3,4-Tetrahydro-acridin-9-ylamino)-heptyl]-isoindole-1,3-dione::2-[7-(1,2,3,4-tetrahydroacridin-9-ylamino)heptyl]-2,3-dihydro-1H-isoindole-1,3-dione::Donepezil-tacrine hybrid 17
SMILES O=C1N(CCCCCCCNc2c3CCCCc3nc3ccccc23)C(=O)c2ccccc12
InChI Key InChIKey=DGQLSDQJMPNFLT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 9068
Affinity DataIC50: 10nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair
Affinity DataIC50: 3.01E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 10 min with...More data for this Ligand-Target Pair