BDBM91592 dUTPase inhibitor, 3

SMILES O=C(OCC1OC(C=C1)n1ccc(=O)[nH]c1=O)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=ZFCNRYHFYSVNPV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 91592   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra

LigandPNGBDBM91592(dUTPase inhibitor, 3)
Affinity DataKi:  5.77E+4nM ΔG°:  -5.78kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra

LigandPNGBDBM91592(dUTPase inhibitor, 3)
Affinity DataKi:  2.98E+5nM ΔG°:  -4.81kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP deaminase(Campylobacter jejuni)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra

LigandPNGBDBM91592(dUTPase inhibitor, 3)
Affinity DataKi:  5.47E+5nM ΔG°:  -4.45kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed