BDBM91656 N-aryl-4-aryl-1,3-thiazole-2-amine, 3
SMILES Oc1ccc(Nc2nc(cs2)-c2ccc(F)cc2)cc1
InChI Key InChIKey=IHEWKLRWCVXDOL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 91656
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
Korea Research Institute of Chemical Technology
Affinity DataIC50: 99nMpH: 7.4 T: 2°CAssay Description:5-LOX enzyme assay was carried out with some modifications of ferric oxidation of xylenol orange (FOX) assay, which is based on the complex formation...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
Korea Research Institute of Chemical Technology
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase in human PMNL using arachidonic acid as substrate preincubated for 15 mins before substrate addition measured after 10 m...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
Korea Research Institute of Chemical Technology
Affinity DataIC50: 60nMAssay Description:Inhibition of partially purified recombinant 5-lipoxygenase (unknown origin) using arachidonic acid as substrate preincubated for 15 mins before subs...More data for this Ligand-Target Pair