BDBM91660 N-aryl-4-aryl-1,3-thiazole-2-amine, 9
SMILES Oc1ccccc1Nc1nc(cs1)-c1ccc(Cl)cc1
InChI Key InChIKey=RLOHGRPRQRYOFC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 91660
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
Korea Research Institute of Chemical Technology
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:5-LOX enzyme assay was carried out with some modifications of ferric oxidation of xylenol orange (FOX) assay, which is based on the complex formation...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
Korea Research Institute of Chemical Technology
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-lipoxygenase in human PMNL using arachidonic acid as substrate preincubated for 15 mins before substrate addition measured after 10 m...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Korea Research Institute of Chemical Technology
Korea Research Institute of Chemical Technology
Affinity DataIC50: 30nMAssay Description:Inhibition of partially purified recombinant 5-lipoxygenase (unknown origin) using arachidonic acid as substrate preincubated for 15 mins before subs...More data for this Ligand-Target Pair