BDBM92739 NSC375491, 12::US9624235, Compound 12

SMILES COc1ccc(C2C3=C(CC(C)(C)CC3=O)Oc3cc4OCOc4cc23)c(OC)c1

InChI Key InChIKey=FHVYASKIUMSUDV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92739   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh

US Patent
LigandPNGBDBM92739(NSC375491, 12 | US9624235, Compound 12)
Affinity DataKi:  3.20E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh

US Patent
LigandPNGBDBM92739(NSC375491, 12 | US9624235, Compound 12)
Affinity DataKi:  3.20E+4nMAssay Description:A fluorescenc-based molecular beacon assay to measure APE-1 protein activity and inhibition was performed as described.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed