BDBM97610 CHEMBL1630715::US8470841, 35

SMILES CC(C)Oc1ccc(Oc2ccc(CC[C@H](C)NC(C)=O)cc2)cn1

InChI Key InChIKey=CHLNWUAMDPEDES-HNNXBMFYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 97610   

TargetAcetyl-CoA carboxylase 2 [151-2458](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50:  190nMpH: 7.5 T: 2°CAssay Description:the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Sanofi

US Patent
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50:  170nMpH: 7.5 T: 2°CAssay Description:the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50:  30nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Sanofi

US Patent
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50:  170nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50:  190nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Sanofi

US Patent
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50:  400nMpH: 7.5 T: 2°CAssay Description:the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.More data for this Ligand-Target Pair
In DepthDetails US Patent