BDBM97617 CHEMBL1629723::US8470841, 46

SMILES COC(=O)NC(C)CCc1ccc(Oc2ccc(OC(C)C)nc2)cc1

InChI Key InChIKey=XZINCLNTAXQIEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 97617   

TargetAcetyl-CoA carboxylase 2 [151-2458](Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM97617(CHEMBL1629723 | US8470841, 46)
Affinity DataIC50:  210nMpH: 7.5 T: 2°CAssay Description:the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM97617(CHEMBL1629723 | US8470841, 46)
Affinity DataIC50:  250nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM97617(CHEMBL1629723 | US8470841, 46)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM97617(CHEMBL1629723 | US8470841, 46)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed