Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with Target = '1,4-dihydroxy-2-naphthoyl-CoA synthase'
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382338BDBM50382338(CHEMBL2024344)
Affinity DataKi:  49nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382339BDBM50382339(CHEMBL2024338)
Affinity DataKi:  97nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382339BDBM50382339(CHEMBL2024338)
Affinity DataIC50: 103nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382338BDBM50382338(CHEMBL2024344)
Affinity DataIC50: 106nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382351BDBM50382351(CHEMBL2024339)
Affinity DataIC50: 135nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382349BDBM50382349(CHEMBL2024341)
Affinity DataIC50: 154nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382352BDBM50382352(CHEMBL2024337)
Affinity DataIC50: 204nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382338BDBM50382338(CHEMBL2024344)
Affinity DataKi:  286nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382337BDBM50382337(CHEMBL2024335)
Affinity DataKi:  350nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382350BDBM50382350(CHEMBL2024340)
Affinity DataIC50: 421nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382337BDBM50382337(CHEMBL2024335)
Affinity DataIC50: 468nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382339BDBM50382339(CHEMBL2024338)
Affinity DataKi:  792nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382337BDBM50382337(CHEMBL2024335)
Affinity DataKi:  1.63E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382346BDBM50382346(CHEMBL2024345)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382341BDBM50382341(CHEMBL2024257)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382342BDBM50382342(CHEMBL2024256)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329094BDBM50329094((Z)-methyl 2-(2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-y...)
Affinity DataKi:  9.10E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329094BDBM50329094((Z)-methyl 2-(2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329084BDBM50329084((Z)-methyl 2-(6-fluoro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataKi:  1.01E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329084BDBM50329084((Z)-methyl 2-(6-fluoro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataKi:  1.15E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382343BDBM50382343(CHEMBL2024255)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382348BDBM50382348(CHEMBL2024342)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382347BDBM50382347(CHEMBL2024343)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382344BDBM50382344(CHEMBL2024254)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329087BDBM50329087((Z)-methyl 2-(6-(ethylsulfonyl)-2-oxo-2H-benzo[b][...)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329088BDBM50329088((Z)-methyl 2-(7-methyl-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329085BDBM50329085((Z)-methyl 2-(6-chloro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataKi:  1.85E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329091BDBM50329091((Z)-methyl 2-(7-nitro-2-oxo-2H-benzo[b][1,4]oxazin...)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329085BDBM50329085((Z)-methyl 2-(6-chloro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataKi:  2.25E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329083BDBM50329083((Z)-methyl 2-(6-methyl-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329082BDBM50329082((Z)-methyl 2-(5-methyl-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329084BDBM50329084((Z)-methyl 2-(6-fluoro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329086BDBM50329086((Z)-methyl 2-(6-nitro-2-oxo-2H-benzo[b][1,4]oxazin...)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329089BDBM50329089((Z)-methyl 2-(7-fluoro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382353BDBM50382353(CHEMBL2024336)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329090BDBM50329090((Z)-methyl 2-(7-chloro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329085BDBM50329085((Z)-methyl 2-(6-chloro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50: 4.63E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382354BDBM50382354(CHEMBL2024253)
Affinity DataIC50: 5.27E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329094BDBM50329094((Z)-methyl 2-(2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-y...)
Affinity DataKi:  6.70E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382354BDBM50382354(CHEMBL2024253)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382344BDBM50382344(CHEMBL2024254)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382340BDBM50382340(CHEMBL2024258)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382341BDBM50382341(CHEMBL2024257)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382340BDBM50382340(CHEMBL2024258)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382343BDBM50382343(CHEMBL2024255)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382342BDBM50382342(CHEMBL2024256)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329092BDBM50329092((Z)-methyl 2-(3-oxo-3,4-dihydroquinoxalin-2(1H)-yl...)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329093BDBM50329093((Z)-methyl 2-(2-oxo-2H-benzo[b][1,4]thiazin-3(4H)-...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382345BDBM50382345(CHEMBL2024346)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed