Compile Data Set for Download or QSAR
Report error Found 956 Enz. Inhib. hit(s) with Target = 'ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1'
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086336BDBM50086336(CHEMBL3426065)
Affinity DataIC50: 0.180nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628841BDBM50628841(CHEMBL5410644)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086433BDBM50086433(CHEMBL3426034)
Affinity DataKi:  0.300nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086438BDBM50086438(CHEMBL3426039)
Affinity DataKi:  0.450nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086432BDBM50086432(CHEMBL3426033)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086436BDBM50086436(CHEMBL3426037)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086434BDBM50086434(CHEMBL3426035)
Affinity DataKi:  0.700nMAssay Description:Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086334BDBM50086334(CHEMBL3426067)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086337BDBM50086337(CHEMBL3426064)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 783081BDBM783081((R)-6-(1H-Imidazol-1-yl)-4-methyl-N-(tetrahydro-2H...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 783105BDBM783105((R)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-2-(1H-i...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 783103BDBM783103((R)-N-(5,5-Difluorotetrahydro-2H-pyran-3-yl)-6-(1H...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 783109BDBM783109(6-(1H-Imidazol-1-yl)-4-methyl-N-(1-((tetrahydrofur...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 783108BDBM783108((R)-N-(4,4-Difluorotetrahydro-2H-pyran-3-yl)-6-(1H...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086350BDBM50086350(CHEMBL3426058)
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 783098BDBM783098(2-(1H-Imidazol-1-yl)-6-methyl-N-(1-(methylsulfonyl...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 783106BDBM783106((R)-2-(1H-Imidazol-1-yl)-6-methyl-N-(tetrahydro-2H...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086335BDBM50086335(CHEMBL3426066)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628837BDBM50628837(CHEMBL5401022)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628840BDBM50628840(CHEMBL5418653)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086431BDBM50086431(CHEMBL3426032)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086336BDBM50086336(CHEMBL3426065)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628835BDBM50628835(CHEMBL5436403)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628844BDBM50628844(CHEMBL5426011)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086438BDBM50086438(CHEMBL3426039)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628836BDBM50628836(CHEMBL5398114)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628846BDBM50628846(CHEMBL5425216)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628843BDBM50628843(CHEMBL5434460)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628845BDBM50628845(CHEMBL5440681)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086434BDBM50086434(CHEMBL3426035)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086437BDBM50086437(CHEMBL3426038)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086433BDBM50086433(CHEMBL3426034)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628838BDBM50628838(CHEMBL5440312)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628848BDBM50628848(CHEMBL5427901)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628842BDBM50628842(CHEMBL5405079)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086439BDBM50086439(CHEMBL3426040)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600833BDBM50600833(CHEMBL5172896)
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse his tagged CD38 using N6-etheno-NAD as substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086337BDBM50086337(CHEMBL3426064)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628851BDBM50628851(CHEMBL5414411)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086436BDBM50086436(CHEMBL3426037)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086432BDBM50086432(CHEMBL3426033)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50600805BDBM50600805(CHEMBL5178786)
Affinity DataIC50: 4nMAssay Description:Inhibition of human his tagged CD38 using N6-etheno-NAD as substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086355BDBM50086355(CHEMBL3426053)
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50461132BDBM50461132(CHEMBL4229241)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human CD38 extracellular domain expressed in Pichia pastoris using NAD as substrate pretreated for 30 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086351BDBM50086351(CHEMBL3426057)
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580354BDBM50580354(CHEMBL5076763)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of His-tagged human CD38 using etheno-NAD as substrate preincubated for 30 mins followed by substrate addition and further incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086424BDBM50086424(CHEMBL3426029)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of mouse recombinant CD38 extracellular domain expressed in CHO CGE cells assessed as NAD hydrolysis by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086335BDBM50086335(CHEMBL3426066)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580351BDBM50580351(CHEMBL5083478)
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human CD38 using etheno-NAD as substrate preincubated for 30 mins followed by substrate addition and further incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Immunophage Biotech Co.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628849BDBM50628849(CHEMBL5424500)
Affinity DataIC50: 5nMAssay Description:Inhibition of human CD38 using epslon-NAD as substrate and measured for 1 hrs by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
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