Report error Found 109 Enz. Inhib. hit(s) with Target = 'Alpha-mannosidase 2'
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nM ΔG°: -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
Affinity DataKi: 4.35E+3nMAssay Description:Inhibition of human golgi alpha mannosidase 2More data for this Ligand-Target Pair
Affinity DataKi: 6.47E+3nMAssay Description:Inhibition of human golgi alpha mannosidase 2More data for this Ligand-Target Pair
Affinity DataKi: 7.77E+3nMAssay Description:Inhibition of human golgi alpha mannosidase 2More data for this Ligand-Target Pair
