Report error Found 845 Enz. Inhib. hit(s) with Target = 'Beta-glucuronidase'
Affinity DataIC50: 1nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human GUSbeta using 4-MUG as substrate pre-incubated for 10 mins followed by substrate addition and measured after 60 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 12nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataKi: 132nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataIC50: 164nMAssay Description:In-vivo inhibition of beta-glucuronidase in BALB/CJ mouse at 10 ug administered as twice dailyMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
