Compile Data Set for Download or QSAR
Report error Found 171 Enz. Inhib. hit(s) with Target = 'CREB-binding protein/Histone acetyltransferase p300'
LigandPNGBDBM50250892(CHEMBL4061254 | US10696655, Example 63 | US1116807...)
Affinity DataEC50:  53nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as reduction in MYC expression after 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
LigandPNGBDBM50250911(CHEMBL4095153 | US10696655, Example 45 | US1116807...)
Affinity DataEC50:  12nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as reduction in MYC expression after 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
LigandPNGBDBM50250896(CHEMBL4065346 | US10696655, Example 52 | US1116807...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as reduction in MYC expression after 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
LigandPNGBDBM50250910(CHEMBL4072630 | US10696655, Example 18 | US1116807...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as reduction in MYC expression after 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
LigandPNGBDBM50250913(CHEMBL4073812 | US10696655, Example 67 | US1116807...)
Affinity DataEC50:  360nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as reduction in MYC expression after 4 hrs by luminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
LigandPNGBDBM50453948(CHEMBL4204490 | US11247989, Example 96)
Affinity DataEC50:  76nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50453950(CHEMBL4203082 | US11247989, Example 88)
Affinity DataEC50:  32nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50453970(CHEMBL4207965 | US11247989, Example 98)
Affinity DataEC50:  110nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50453971(CHEMBL4204065 | US11247989, Example 11)
Affinity DataEC50:  280nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataEC50:  18nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50453957(CHEMBL4217213)
Affinity DataEC50:  6.60nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50453976(CHEMBL4209361 | US11247989, Example 97)
Affinity DataEC50:  220nMAssay Description:Inhibition of P300/CBP in human MV4-11 cells assessed as downregulation of MYC expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50586503(CHEMBL5074760)
Affinity DataKd:  21nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586504(CHEMBL5084183)
Affinity DataKd:  34nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586505(CHEMBL5081656)
Affinity DataKd:  30nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586506(CHEMBL5092869)
Affinity DataKd:  22nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586507(CHEMBL5088177)
Affinity DataKd:  32nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586508(CHEMBL5080878)
Affinity DataKd:  36nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586509(CHEMBL5088540)
Affinity DataKd:  226nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586510(CHEMBL5077289)
Affinity DataKd:  1.54E+3nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586511(CHEMBL5090131)
Affinity DataKd:  18nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586512(CHEMBL5074479)
Affinity DataKd:  228nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586513(CHEMBL5087442)
Affinity DataKd:  37nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50586514(CHEMBL5076857)
Affinity DataKd:  313nMAssay Description:Binding affinity to His-tagged human CH1 domain of p300 (323 to 423 residues)expressed in Escherichia coli Rosetta (DE3)/CBP (unknown origin) by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandPNGBDBM50607577(CHEMBL5219851)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607578(CHEMBL5218485)
Affinity DataEC50:  5.01E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607579(CHEMBL5219575)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607580(CHEMBL5218875)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607581(CHEMBL5221117)
Affinity DataEC50:  5.01E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607582(CHEMBL5220135)
Affinity DataEC50:  7.94E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607583(CHEMBL5218882)
Affinity DataEC50:  5.01E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607584(CHEMBL5221088)
Affinity DataEC50:  5.01E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607585(CHEMBL5219512)
Affinity DataEC50:  251nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607586(CHEMBL5221030)
Affinity DataEC50:  316nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607587(CHEMBL5219253)
Affinity DataEC50: <5.01E+4nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607588(CHEMBL5220546)
Affinity DataEC50:  501nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607589(CHEMBL5219678)
Affinity DataEC50:  316nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607590(CHEMBL5220332)
Affinity DataEC50:  200nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607591(CHEMBL5219472)
Affinity DataEC50:  3.98E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607592(CHEMBL5219466)
Affinity DataEC50:  501nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607593(CHEMBL5219693)
Affinity DataEC50:  13nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607594(CHEMBL5219204)
Affinity DataEC50:  3.16E+3nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607595(CHEMBL5219030)
Affinity DataEC50:  50nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607596(CHEMBL5221053)
Affinity DataEC50:  40nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607597(CHEMBL5219157)
Affinity DataEC50:  100nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607598(CHEMBL5220447)
Affinity DataEC50:  79nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607599(CHEMBL5220732)
Affinity DataEC50:  50nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607600(CHEMBL5220956)
Affinity DataEC50:  16nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607601(CHEMBL5219667)
Affinity DataEC50:  6.30nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50607602(CHEMBL5220994)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
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