Found 2 Enz. Inhib. hit(s) with Target = 'CREB-binding protein/Histone acetyltransferase p300' and Ligand = 'BDBM188519' TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Ludwig-Maximilians-Universit£T M£Nchen
Curated by ChEMBL
Ludwig-Maximilians-Universit£T M£Nchen
Curated by ChEMBL
Affinity DataKd: 21nMAssay Description:Binding affinity to human N-terminal His10-tagged/C-terminal Biotin-tagged CBP (R1081 to G1198 residues)/P300 expressed in Escherichia coli BL21(DE3)...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Ludwig-Maximilians-Universit£T M£Nchen
Curated by ChEMBL
Ludwig-Maximilians-Universit£T M£Nchen
Curated by ChEMBL
Affinity DataEC50: 6.90E+3nMAssay Description:Inhibition of CBP/EP300 (unknown origin) assessed as reduction in MYC expression by cell based assayMore data for this Ligand-Target Pair
