Compile Data Set for Download or QSAR
Report error Found 14074 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 2'
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353092(CHEMBL1822945)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353089(CHEMBL1822939)
Affinity DataKi:  0.0140nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50272395(N-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-...)
Affinity DataEC50:  0.0150nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50308541(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  0.0190nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50308541(7-Methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3...)
Affinity DataKi:  0.0190nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353091(CHEMBL1822944)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353091(CHEMBL1822944)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353091(CHEMBL1822944)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073061(CHEMBL3410832)
Affinity DataKi:  0.0210nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073061(CHEMBL3410832)
Affinity DataKi:  0.0210nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353086(CHEMBL1822940)
Affinity DataKi:  0.0210nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50180036(CHEMBL371214 | (6aR,10aR)-3-(1,1-dimethylbutyl)-6a...)
Affinity DataKi:  0.0230nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073068(CHEMBL3410813)
Affinity DataKi:  0.0260nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073068(CHEMBL3410813)
Affinity DataKi:  0.0260nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50006257(CHEMBL3233404)
Affinity DataKi:  0.0320nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353093(CHEMBL1822946)
Affinity DataKi:  0.0320nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50330773(JWH-051 | CHEMBL1277685 | ((6aR,10aR)-6,6-dimethyl...)
Affinity DataKi:  0.0320nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50454329(CHEMBL2112647)
Affinity DataKi:  0.0320nMAssay Description:Ability to bind with Cannabinoid receptor 2 using [H]CP-55940 as radioligand from cloned human receptor preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353087(CHEMBL1822941)
Affinity DataKi:  0.0360nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200169(6-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.0370nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200169(6-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.0370nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50200169(6-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.0370nMAssay Description:Displacement of [3H]CP-55,940 from CB2 receptor in CD-1 mouse spleen homogenate after 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50006258(CHEMBL3234701)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at human CB2 receptor assessed as inhibition of forskolin-induced cAMP production preincubated for 15 mins followed by forskolin cha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM21280(N-(1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-...)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50200169(6-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50063927(CHEMBL3400946)
Affinity DataEC50:  0.0400nMAssay Description:Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50200169(6-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]CP-55940 from CD1 mouse spleen CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353088(CHEMBL1822942)
Affinity DataKi:  0.0430nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM21280(N-(1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50072968(CHEMBL3410818)
Affinity DataKi:  0.0530nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50072968(CHEMBL3410818)
Affinity DataKi:  0.0530nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50006259(CHEMBL3234706)
Affinity DataEC50:  0.0670nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50006259(CHEMBL3234706)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50006259(CHEMBL3234706)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at human recombinant CB2 receptor expressing CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303551(3-(2-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-...)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at rat CB2 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50006259(CHEMBL3234706)
Affinity DataEC50:  0.0700nMAssay Description:Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50404173(CHEMBL5266788)
Affinity DataKi:  0.0750nMAssay Description:Antagonist activity at human CB2R assessed as beta arrestin-2 recruitment by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50000727((R)-3-(1,1-Dimethyl-heptyl)-9-hydroxymethyl-6,6-di...)
Affinity DataEC50:  0.0780nMAssay Description:Effective concentration for inhibition of human Cannabinoid receptor 2-mediated adenylyl cyclase using African green monkey (COS-7) cells transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50404173(CHEMBL5266788)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 90 mins by radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50288371(CHEMBL4177060 | US11472787, Compound 10,11-EDP-IA)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50288371(CHEMBL4177060 | US11472787, Compound 10,11-EDP-IA)
Affinity DataEC50:  0.0800nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50063924(CHEMBL3400943)
Affinity DataEC50:  0.0800nMAssay Description:Inhibition of human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353090(CHEMBL1822943)
Affinity DataKi:  0.0849nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353090(CHEMBL1822943)
Affinity DataKi:  0.0850nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50353090(CHEMBL1822943)
Affinity DataKi:  0.0850nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073005(CHEMBL3410729)
Affinity DataKi:  0.0869nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM85739(N-(1,3-Benzodioxole-5-ylmethyl)-2-oxo-7-methoxy-8-...)
Affinity DataKi:  0.0870nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073005(CHEMBL3410729)
Affinity DataKi:  0.0870nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073000(CHEMBL3410826)
Affinity DataKi:  0.0879nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50073000(CHEMBL3410826)
Affinity DataKi:  0.0880nMAssay Description:Binding affinity to CB2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2016
Entry Details Article
PubMed
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