Compile Data Set for Download or QSAR
Report error Found 789 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A'
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274136BDBM50274136(CHEMBL4126781)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274145BDBM50274145(CHEMBL4127930)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274126BDBM50274126(CHEMBL4127938)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274128BDBM50274128(CHEMBL4127899)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274129BDBM50274129(CHEMBL4126667)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274133BDBM50274133(CHEMBL4129139)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274134BDBM50274134(CHEMBL4128711)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50494813BDBM50494813(CHEMBL3094348)
Affinity DataIC50: 2.38nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274135BDBM50274135(CHEMBL4129934)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274127BDBM50274127(CHEMBL4129335)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266345BDBM50266345(CHEMBL4094690)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266347BDBM50266347(CHEMBL4070524)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226181BDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572196BDBM50572196(CHEMBL4879265)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266348BDBM50266348(CHEMBL4064539)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266393BDBM50266393(CHEMBL4099988)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572198BDBM50572198(CHEMBL4873479)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266374BDBM50266374(CHEMBL4099469)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572194BDBM50572194(CHEMBL4862136)
Affinity DataIC50: 6nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572195BDBM50572195(CHEMBL4868908)
Affinity DataIC50: 7nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24609BDBM24609(3-ethyl-1-[7-(pyridin-2-yl)-5-(pyridin-3-yl)-1H-1,...)
Affinity DataKi:  7nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274132BDBM50274132(CHEMBL4127740)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518949BDBM50518949(CHEMBL4448131)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266344BDBM50266344(CHEMBL4061762)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266351BDBM50266351(CHEMBL4096181)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266352BDBM50266352(CHEMBL4086015)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266355BDBM50266355(CHEMBL4066198)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266342BDBM50266342(CHEMBL4101490)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266356BDBM50266356(CHEMBL4074808)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266378BDBM50266378(CHEMBL4066059)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24606BDBM24606(methyl 2-[(ethylcarbamoyl)amino]-5-(pyridin-3-yl)-...)
Affinity DataKi:  8nM ΔG°:  -47.0kJ/molepH: 7.5 T: 2°CAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266379BDBM50266379(CHEMBL4083966)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266349BDBM50266349(CHEMBL4092234)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266350BDBM50266350(CHEMBL4091332)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266394BDBM50266394(CHEMBL4070393)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266343BDBM50266343(CHEMBL4078126)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266366BDBM50266366(CHEMBL4091200)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266367BDBM50266367(CHEMBL4071960)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266368BDBM50266368(CHEMBL4098937)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266369BDBM50266369(CHEMBL4087439)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266370BDBM50266370(CHEMBL4081451)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266375BDBM50266375(CHEMBL4100423)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330317BDBM50330317(5-Methyl-1H-pyrrole-2-carboxylic acid (3R,4S,5R,6S...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50406470BDBM50406470(Kibdelomycin)
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572199BDBM50572199(CHEMBL4866999)
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572200BDBM50572200(CHEMBL4862951)
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393079BDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  9nMpH: 7.6Assay Description:The ATP hydrolysis activity of S. aureus DNA gyrase is measured by coupling the production of ADP through pyruvate kinase/lactate dehydrogenase to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
US Patent

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572201BDBM50572201(CHEMBL4864750)
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393079BDBM50393079(CHEMBL2152855 | US9040542, 23)
Affinity DataKi:  9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using pBR322 plasmid DNA as substrate by coupled enzyme reaction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Bharathiar University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274131BDBM50274131(CHEMBL4128159)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
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