Compile Data Set for Download or QSAR
Report error Found 176 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor 2'
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM142256(US8933099, 22 | US9951047, Compound (I))
Affinity DataIC50: 4.5nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR2 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50073748(CHEMBL3559508)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063776(CHEMBL3397498)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM142255(US8933099, 21)
Affinity DataIC50: 5.10nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR2 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50073747(CHEMBL3409457)
Affinity DataKd:  5.20nMAssay Description:Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50073750(CHEMBL3409454)
Affinity DataKd:  5.60nMAssay Description:Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM142236(US8933099, 2)
Affinity DataIC50: 6.40nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR2 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50073749(CHEMBL3409455)
Affinity DataKd:  8.20nMAssay Description:Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063847(CHEMBL3397488)
Affinity DataKd:  16nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50073751(CHEMBL3409453)
Affinity DataKd:  16nMAssay Description:Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063824(CHEMBL3397494)
Affinity DataKd:  21nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063843(CHEMBL3397491)
Affinity DataKd:  23nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063848(CHEMBL3397487)
Affinity DataKd:  25nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50000130(CHEMBL320550)
Affinity DataIC50: 25.2nMAssay Description:24% inhibition of FGF-2 binding to heparin-albumin by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307389(2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosyl-(1->3...)
Affinity DataKd:  35nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063850(CHEMBL3397485)
Affinity DataKd:  36nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50388343(CHEMBL2059243)
Affinity DataKd:  39nMAssay Description:Binding affinity to FGF-2 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063846(CHEMBL3397489)
Affinity DataKd:  41nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063844(CHEMBL3397490)
Affinity DataKd:  41nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307387(8-(4-Phenyl[1,2,3]triazol-1-yl)octyl 2,3,4,6-Tetra...)
Affinity DataKd:  43nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50073810(CHEMBL3559507)
Affinity DataKd:  48nMAssay Description:Binding affinity to FGF2 (unknown origin) assessed as change in luminance intensity at at 25 degC by SPR imaging sensor methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50388333(CHEMBL2059502)
Affinity DataKd:  50nMAssay Description:Binding affinity to FGF-2 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063810(CHEMBL3397496)
Affinity DataKd:  52nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063812(CHEMBL3397495)
Affinity DataKd:  60nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50378647(PI-88 | CHEMBL1627122)
Affinity DataKd:  61nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063849(CHEMBL3397486)
Affinity DataKd:  62nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50179253((2R,3S,4S,5S,6R)-2-{[(2R,3S,4S,5R,6R)-2-{[(2R,3S,4...)
Affinity DataKd:  68nMAssay Description:Binding affinity for FGF2 by BIAcore solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307396(12-(4-Naphthalen-1-yl[1,2,3]triazol-1-yl)dodecyl 2...)
Affinity DataKd:  73nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307400(hexadecasodium [3-({4-[(4-{[3,5-bis(sulfonatooxy)-...)
Affinity DataKd:  82nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307392(3-(4-Phenyl[1,2,3]triazol-1-yl)propyl 2,3,4,6-Tetr...)
Affinity DataKd:  83nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50179256(6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d...)
Affinity DataKd:  84nMAssay Description:Binding affinity for FGF2 by BIAcore solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM84571(Linked sulfated tetracyclitol, 12)
Affinity DataKd:  85nMpH: 7.4Assay Description:Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50179254((2R,3S,4S,5S,6R)-2-{[(2R,3S,4S,5R,6R)-2-{[(2R,3S,4...)
Affinity DataKd:  86nMAssay Description:Binding affinity for FGF2 by BIAcore solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307394(3-(5-Dimethylaminonaphthalene-1-sulfonamido)propyl...)
Affinity DataKd:  86nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM84566(Linked sulfated tetracyclitol, 7)
Affinity DataKd:  90nMpH: 7.4Assay Description:Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063835(CHEMBL3397493)
Affinity DataKd:  95nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307398(Hexadecasodium [2-(benzyloxy)-3-({4-[(4-{[3,5-bis(...)
Affinity DataKd:  95nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50063808(CHEMBL3397497)
Affinity DataKd:  99nMAssay Description:Binding affinity to basic fibroblast growth factor (unknown origin) using sugar chip immobilized compound by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM167952(1-(4-(3-Methoxyphenyl)piperazin-1-yl)-3-(quinazoli...)
Affinity DataIC50: 103nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50388342(CHEMBL2059242)
Affinity DataKd:  108nMAssay Description:Binding affinity to FGF-2 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM84567(Linked sulfated tetracyclitol, 8)
Affinity DataKd:  108nMpH: 7.4Assay Description:Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307390(8-(4-Naphthalen-1-yl[1,2,3]triazol-1-yl)octyl 2,3,...)
Affinity DataKd:  110nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50179255(N-[(2S,3S,4S,5S,6R)-3-{[(2R,3S,4S,5R,6R)-4-{[(2R,3...)
Affinity DataKd:  112nMAssay Description:Binding affinity for FGF2 by BIAcore solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50331095(Tivozanib | CHEMBL1289494 | US10464902, Tivozanib)
Affinity DataIC50: 114nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM167953(1-(4-(4-Methoxyphenyl)piperazin-1-yl)-3-(quinazoli...)
Affinity DataIC50: 122nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307399(Benzyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosy...)
Affinity DataKd:  129nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307391(8-(5-Dimethylaminonaphthalene-1-sulfonamido)octyl ...)
Affinity DataKd:  130nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM84565(Linked sulfated tetracyclitol, 6)
Affinity DataKd:  135nMpH: 7.4Assay Description:Human FGF-1 and FGF-2 were purchased from R&D Systems, Inc. and supplied as protein (ug) dissolved in bovine serum albumin (BSA, 50ug). Surface plas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM50307388(8-(4-Phenyl[1,2,3]triazol-1-yl)octyl 2,3,4,6-Tetra...)
Affinity DataKd:  140nMAssay Description:Binding affinity to FGF2 by surface plasmon-based solution affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetFibroblast growth factor 23(Human)
Tennessee Technological University

Curated by ChEMBL
LigandPNGBDBM50549239(CHEMBL4755048)
Affinity DataIC50: 140nMAssay Description:Inhibition of FGF23 (unknown origin)-mediated activation of FGFR/alpha-Klotho transfected in HEK293T cells cotransfected with ERK luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
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