Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with Target = 'G1/S-specific cyclin-E1'
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246253BDBM50246253(AZD-5438 | 4-(1-isopropyl-2-methyl-1H-imidazol-5-y...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Cyclin E/CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  15nMAssay Description:Binding affinity to human CCNE1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  75nMAssay Description:Binding affinity to human CCNE1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 59097BDBM59097(Aminopyrimidine, 10)
Affinity DataIC50: 220nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50319624BDBM50319624(Aminopyrimidine, 4 | CHEMBL1084454 | N1-(4-(2,4-Di...)
Affinity DataIC50: 230nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 59092BDBM59092(Aminopyrimidine, 2)
Affinity DataIC50: 330nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 59091BDBM59091(Aminopyrimidine, 1)
Affinity DataIC50: 410nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 59093BDBM59093(Aminopyrimidine, 3)
Affinity DataIC50: 430nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50277583BDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 59095BDBM59095(Aminopyrimidine, 7)
Affinity DataIC50: 1.02E+3nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 59094BDBM59094(Aminopyrimidine, 6)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50319619BDBM50319619(Aminopyrimidine, 5 | CHEMBL1085626 | 4-(2,4-Dimeth...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed
TargetG1/S-specific cyclin-E1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 59096BDBM59096(Aminopyrimidine, 8)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro kinase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2011
Entry Details Article
PubMed