Compile Data Set for Download or QSAR
Report error Found 606 Enz. Inhib. hit(s) with Target = 'Heparanase'
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614394BDBM50614394(CHEMBL5273238)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human heparanase using fondaparinux as substrate incubated for 18 hrs by Polymer-H fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614394BDBM50614394(CHEMBL5273238)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388329BDBM50388329(CHEMBL2059500)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611959BDBM50611959(CHEMBL5276024)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human heparanase incubated for 4 hrs by beta-scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466629BDBM50466629(CHEMBL4280766)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388343BDBM50388343(CHEMBL2059243)
Affinity DataKi:  5.5nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388341BDBM50388341(CHEMBL2059241)
Affinity DataKi:  5.80nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614397BDBM50614397(CHEMBL5279386)
Affinity DataKi:  6nMAssay Description:Binding affinity to heparanase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388342BDBM50388342(CHEMBL2059242)
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388331BDBM50388331(CHEMBL2059499)
Affinity DataKi:  6.10nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388345BDBM50388345(CHEMBL2059245)
Affinity DataKi:  6.40nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378647BDBM50378647(PI-88 | CHEMBL1627122)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388332BDBM50388332(CHEMBL2059498)
Affinity DataKi:  8.40nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388346BDBM50388346(CHEMBL2059246)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388336BDBM50388336(CHEMBL2059504)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388335BDBM50388335(CHEMBL2059503)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388330BDBM50388330(CHEMBL2059247)
Affinity DataKi:  10.5nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388328BDBM50388328(CHEMBL2059505)
Affinity DataKi:  11.3nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614397BDBM50614397(CHEMBL5279386)
Affinity DataIC50: 12nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612819BDBM50612819(CHEMBL5291042)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human HPSE expressed in insect cells by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611973BDBM50611973(CHEMBL5282692)
Affinity DataIC50: 12nMAssay Description:Inhibition of HPSE (unknown origin) using fondaparinux as substrate incubated for 18 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388334BDBM50388334(CHEMBL2059501)
Affinity DataKi:  16nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431651BDBM50431651(CHEMBL2349236)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093526BDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614398BDBM50614398(CHEMBL5268939)
Affinity DataIC50: 20nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611974BDBM50611974(CHEMBL5271999)
Affinity DataIC50: 20nMAssay Description:Inhibition of HPSE (unknown origin) using fondaparinux as substrate incubated for 18 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612820BDBM50612820(CHEMBL5267246)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HPSE expressed in insect cells by fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388333BDBM50388333(CHEMBL2059502)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640013BDBM50640013(CHEMBL5562364)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640011BDBM50640011(CHEMBL5559476)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388344BDBM50388344(CHEMBL2059244)
Affinity DataKi:  22.3nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640010BDBM50640010(CHEMBL5561988)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640009BDBM50640009(CHEMBL5549928)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388340BDBM50388340(CHEMBL2059510)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640004BDBM50640004(CHEMBL5557429)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640007BDBM50640007(CHEMBL5556661)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640012BDBM50640012(CHEMBL5557768)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640006BDBM50640006(CHEMBL5559840)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640003BDBM50640003(CHEMBL5564261)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647174BDBM50647174(CHEMBL5597984)
Affinity DataIC50: 57nMAssay Description:Inhibition of HPSE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175932BDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50175932BDBM50175932(1,3-bis-[4-(5,6-dimethyl-1H-benzoimidazol-2-yl)phe...)
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against heparanase from human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466636BDBM50466636(CHEMBL4286441)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant HPSE (unknown origin) using fondaparinux as substrate incubated for 3 hrs in absence of light by WST1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640005BDBM50640005(CHEMBL5560024)
Affinity DataIC50: 82nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640008BDBM50640008(CHEMBL5559647)
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640002BDBM50640002(CHEMBL5561039)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human heparanase expressed in Insect cells assessed as fondaparinux cleavage by measuring disaccharide product incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50104680BDBM50104680(3-Hexadecanoyl-5-hydroxymethyl-4-methoxy-5H-furan-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611970BDBM50611970(CHEMBL5286960)
Affinity DataIC50: 100nMAssay Description:Inhibition of HPSE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50388338BDBM50388338(CHEMBL2059508)
Affinity DataKi:  111nMAssay Description:Inhibition of human recombinant heparanase after 2 to 24 hrs by WST1 dye based fondaparinux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHeparanase(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618639BDBM50618639(CHEMBL5432881)
Affinity DataIC50: 120nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
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