Compile Data Set for Download or QSAR
Report error Found 432 Enz. Inhib. hit(s) with Target = 'Inositol hexakisphosphate kinase 1'
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647694BDBM50647694(CHEMBL5598155 | US20250346572, Example 30)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647666BDBM50647666(CHEMBL5598038)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605476BDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647707BDBM50647707(CHEMBL5596194 | US20250346572, Example 52)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647716BDBM50647716(CHEMBL5590726 | US20250346572, Example 61)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647712BDBM50647712(CHEMBL5598068 | US20250346572, Example 57)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647719BDBM50647719(CHEMBL5598514 | US20250346572, Example 64)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647685BDBM50647685(CHEMBL5597913 | US20250346572, Example 34)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647693BDBM50647693(CHEMBL5596094 | US20250346572, Example 29)
Affinity DataIC50: 8nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605476BDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inhibition of [3H]-InsP6 phosphorylation m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647687BDBM50647687(CHEMBL5598435 | US20250346572, Example 36)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739877BDBM739877(US20250154115, Compound 85)
Affinity DataIC50: 10nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739920BDBM739920(US20250154115, Compound 130)
Affinity DataIC50: 10nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647706BDBM50647706(CHEMBL5597090 | US20250346572, Example 46)
Affinity DataIC50: 16nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647720BDBM50647720(CHEMBL5590042 | US20250346572, Example 65)
Affinity DataIC50: 16nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605488BDBM50605488(CHEMBL5169462 | US20250154115, Compound 57)
Affinity DataIC50: 26nMAssay Description:Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605484BDBM50605484(CHEMBL5181623 | US20250154115, Compound 16)
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647690BDBM50647690(CHEMBL5598271 | US20250346572, Example 28)
Affinity DataIC50: 27nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605510BDBM50605510(CHEMBL5203174 | US20250197396, Compound 2a)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant full length human IP6K1 assessed as inorganic phosphate release measured after 30 mins by ADP-Glo Max assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647655BDBM50647655(CHEMBL5596469)
Affinity DataIC50: 28nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647672BDBM50647672(CHEMBL5597088 | US20250346572, Example 7)
Affinity DataIC50: 28nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647708BDBM50647708(CHEMBL5596929 | US20250346572, Example 53)
Affinity DataIC50: 30nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647658BDBM50647658(US20250197396, Compound 16a)
Affinity DataIC50: 31nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647696BDBM50647696(CHEMBL5596184 | US20250346572, Example 32)
Affinity DataIC50: 35nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647675BDBM50647675(CHEMBL5596237 | US20250346572, Example 9)
Affinity DataIC50: 36nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647686BDBM50647686(CHEMBL5596303)
Affinity DataIC50: 39nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647697BDBM50647697(CHEMBL5597391)
Affinity DataIC50: 43nMAssay Description:Inhibition of IP6K1 (unknown origin) using IP6 as substrate incubated for 30 mins in presence of ATP by ADPGlo enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739882BDBM739882(US20250154115, Compound 90)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647675BDBM50647675(CHEMBL5596237 | US20250346572, Example 9)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647673BDBM50647673(CHEMBL5596496 | US20250346572, Example 8)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647672BDBM50647672(CHEMBL5597088 | US20250346572, Example 7)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605476BDBM50605476(CHEMBL5190343 | US20250154115, Compound 20)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739881BDBM739881(US20250154115, Compound 89)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739880BDBM739880(US20250154115, Compound 88)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739886BDBM739886(US20250154115, Compound 94)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739884BDBM739884(US20250154115, Compound 92)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50647681BDBM50647681(CHEMBL5596764 | US20250346572, Example 14)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605488BDBM50605488(CHEMBL5169462 | US20250154115, Compound 57)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739883BDBM739883(US20250154115, Compound 91)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605484BDBM50605484(CHEMBL5181623 | US20250154115, Compound 16)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739876BDBM739876(US20250154115, Compound 84)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739875BDBM739875(US20250154115, Compound 83)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605509BDBM50605509(CHEMBL5204881 | US20250154115, Compound 19)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739879BDBM739879(US20250154115, Compound 87)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739878BDBM739878(US20250154115, Compound 86)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739809BDBM739809(US20250154115, Compound 17)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739856BDBM739856(US20250154115, Compound 64)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739902BDBM739902(US20250154115, Compound 112)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 739901BDBM739901(US20250154115, Compound 111)
Affinity DataIC50: 55nMAssay Description:Enzyme activity was assayed at 37° C. in 50 μL reaction mixtures containing 100 nM IP6K1 or IP6K2, or 200 nM IP6K3, and unless otherwise indicated, 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInositol hexakisphosphate kinase 1(Human)
Johns Hopkins School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 785492BDBM785492(Cis-4-[(3,5-dichloro-2-pyridyl)oxy]- 5'-(2-oxo-3H-...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/4/2026
Entry Details US Patent

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