Compile Data Set for Download or QSAR
Report error Found 391 Enz. Inhib. hit(s) with Target = 'Isoform 1 of Metabotropic glutamate receptor 5 (5a)'
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174091BDBM174091(US9688669, Example 1)
Affinity DataEC50:  1.70nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174092BDBM174092(US9688669, Example 2)
Affinity DataEC50:  2nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174100BDBM174100(US9688669, Example 3)
Affinity DataEC50:  2.20nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174125BDBM174125(US9688669, Example 4)
Affinity DataEC50:  3.60nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174127BDBM174127(US9688669, Example 5)
Affinity DataEC50:  4.70nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174129BDBM174129(US9688669, Example 6)
Affinity DataEC50:  5.20nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174131BDBM174131(US9688669, Example 7)
Affinity DataEC50:  5.90nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222833BDBM222833(US9315498, 124)
Affinity DataEC50:  7nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222718BDBM222718(US9315498, 5)
Affinity DataEC50:  7nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174195BDBM174195(US9688669, Example 51)
Affinity DataEC50:  8.10nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174258BDBM174258(US9688669, Example 89)
Affinity DataEC50:  8.30nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222719BDBM222719(US9315498, 6)
Affinity DataEC50:  9nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174201BDBM174201(US9688669, Example 52)
Affinity DataEC50:  9.30nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198916BDBM198916(US9221802, Ex. 2)
Affinity DataEC50:  10nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198910BDBM198910(US9221802, Ref. Ex. 72 | US9315498, 72)
Affinity DataEC50:  10nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198910BDBM198910(US9221802, Ref. Ex. 72 | US9315498, 72)
Affinity DataEC50:  10nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198917BDBM198917(US9221802, Ex. 3)
Affinity DataEC50:  10nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174231BDBM174231(US9688669, Example 62)
Affinity DataEC50:  11nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222831BDBM222831(US9315498, 122)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174133BDBM174133(US9688669, Example 9)
Affinity DataEC50:  11nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222794BDBM222794(US9315498, 84)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222828BDBM222828(US9315498, 119)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222746BDBM222746(US9315498, 34)
Affinity DataEC50:  11nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222789BDBM222789(US9315498, 77)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198913BDBM198913(US9221802, Ref. Ex. 81 | US9315498, 81)
Affinity DataEC50:  12nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174232BDBM174232(US9688669, Example 63)
Affinity DataEC50:  12nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222775BDBM222775(US9315498, 62)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222888BDBM222888(US9315498, 174)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222755BDBM222755(US9315498, 43)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174132BDBM174132(US9688669, Example 8 | US9688669, Example 10)
Affinity DataEC50:  12nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222735BDBM222735(US9315498, 23)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222797BDBM222797(US9315498, 87)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198913BDBM198913(US9221802, Ref. Ex. 81 | US9315498, 81)
Affinity DataEC50:  12nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222834BDBM222834(US9315498, 125)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198911BDBM198911(US9221802, Ref. Ex. 76 | US9315498, 76)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222883BDBM222883(US9315498, 169)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222884BDBM222884(US9315498, 170)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 198911BDBM198911(US9221802, Ref. Ex. 76 | US9315498, 76)
Affinity DataEC50:  13nMT: 2°CAssay Description:About 24 hrs before an experiment, 5x104 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174132BDBM174132(US9688669, Example 8 | US9688669, Example 10)
Affinity DataEC50:  13nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222827BDBM222827(US9315498, 118)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222824BDBM222824(US9315498, 115)
Affinity DataEC50:  13nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 168300BDBM168300(US9688669, Example 99)
Affinity DataEC50:  13nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222867BDBM222867(US9315498, 153)
Affinity DataEC50:  14nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174135BDBM174135(US9688669, Example 11)
Affinity DataEC50:  14nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222734BDBM222734(US9315498, 22)
Affinity DataEC50:  14nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222760BDBM222760(US9315498, 48)
Affinity DataEC50:  14nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222741BDBM222741(US9315498, 29)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 174233BDBM174233(US9688669, Example 64 | US9688669, Example 66 | US...)
Affinity DataEC50:  15nMAssay Description:HEK293 (ZF) cells stably transfected with human mGluR5A (pIRES neo) and the rat glutamate-aspartate transporter (GLAST; pIRES puro) are grown in a mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222722BDBM222722(US9315498, 9)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 222752BDBM222752(US9315498, 40)
Affinity DataEC50:  15nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

Displayed 1 to 50 (of 391 total ) | Next | Last >>
Jump to: