Compile Data Set for Download or QSAR
Report error Found 348 Enz. Inhib. hit(s) with Target = 'Isoleucine--tRNA ligase'
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471296BDBM50471296(CHEMBL87935)
Affinity DataIC50: 0.700nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50290686BDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataIC50: 0.800nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290686BDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataIC50: 0.850nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471292BDBM50471292(CHEMBL315230)
Affinity DataIC50: 1.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524451BDBM50524451(CHEMBL4553017)
Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471294BDBM50471294(CHEMBL276855)
Affinity DataIC50: 1.90nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50222902BDBM50222902(CHEMBL1163069)
Affinity DataKi:  1.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471297BDBM50471297(CHEMBL424608)
Affinity DataIC50: 2.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50290686BDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataKi:  2.5nMAssay Description:Competitive inhibition of Escherichia coli Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471293BDBM50471293(CHEMBL83449)
Affinity DataIC50: 3.60nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470911BDBM50470911(CHEMBL122825)
Affinity DataIC50: 4.45nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217841BDBM50217841(REVEROMYCIN A)
Affinity DataIC50: 4.46nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471295BDBM50471295(CHEMBL312853)
Affinity DataIC50: 5.30nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471291BDBM50471291(CHEMBL83394)
Affinity DataIC50: 6nMAssay Description:Inhibition concentration against isoleucyl tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470914BDBM50470914(CHEMBL120343)
Affinity DataIC50: 6.67nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus NCTC 3571More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524451BDBM50524451(CHEMBL4553017)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470913BDBM50470913(CHEMBL120798)
Affinity DataIC50: 6.87nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470912BDBM50470912(CHEMBL120437)
Affinity DataIC50: 7.98nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093003BDBM50093003((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50366870BDBM50366870(CHEMBL605376)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075058BDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524360BDBM50524360(CHEMBL3265242)
Affinity DataKi:  17nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479281BDBM50479281(2,3-DIHYDROREVEROMYCIN A)
Affinity DataIC50: 17.5nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726177BDBM726177(US12247004, Compound ANASIA-041-1)
Affinity DataIC50: 17.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726265BDBM726265(US12247004, Compound ANASIA-103-1)
Affinity DataIC50: 19.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50075061BDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726297BDBM726297(US12247004, Compound ANASIA-124-1)
Affinity DataIC50: 21.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50479274BDBM50479274(4-HYDROXY REVEROMYCIN A)
Affinity DataIC50: 21.7nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726132BDBM726132(US12247004, Compound ANASIA-011-1)
Affinity DataIC50: 26.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726113BDBM726113(US12247004, Compound ANASIA-002-1)
Affinity DataIC50: 27.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726261BDBM726261(US12247004, Compound ANASIA-100-1)
Affinity DataIC50: 27.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726251BDBM726251(US12247004, Compound ANASIA-095-1)
Affinity DataIC50: 29nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50075056BDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075059BDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726126BDBM726126(US12247004, Compound ANASIA-008-1)
Affinity DataIC50: 30.6nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726260BDBM726260(US12247004, Compound ANASIA-100)
Affinity DataIC50: 32.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726230BDBM726230(US12247004, Compound ANASIA-081-1)
Affinity DataIC50: 33.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50075058BDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479284BDBM50479284(CHEMBL442945)
Affinity DataIC50: 36.9nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093001BDBM50093001((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-3-methyl-butyryl...)
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50366862BDBM50366862(CHEMBL605592)
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075056BDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075056BDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726292BDBM726292(US12247004, Compound ANASIA-121-1)
Affinity DataIC50: 41.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50075070BDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726206BDBM726206(US12247004, Compound ANASIA-062-1)
Affinity DataIC50: 47.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 726247BDBM726247(US12247004, Compound ANASIA-092-1)
Affinity DataIC50: 48.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075058BDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 50nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075067BDBM50075067(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 54nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50524354BDBM50524354(CHEMBL3265243)
Affinity DataKi:  55nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
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