Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with Target = 'Isoleucine--tRNA ligase, cytoplasmic'
LigandChemical structure of BindingDB Monomer ID 50290686BDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataIC50: 0.800nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50217841BDBM50217841(REVEROMYCIN A)
Affinity DataIC50: 4.46nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50366870BDBM50366870(CHEMBL605376)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075058BDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479281BDBM50479281(2,3-DIHYDROREVEROMYCIN A)
Affinity DataIC50: 17.5nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075061BDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479274BDBM50479274(4-HYDROXY REVEROMYCIN A)
Affinity DataIC50: 21.7nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075056BDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075059BDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075058BDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479284BDBM50479284(CHEMBL442945)
Affinity DataIC50: 36.9nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50366862BDBM50366862(CHEMBL605592)
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075056BDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075070BDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479277BDBM50479277(2,3-DIHYDRO-5-EPIREVEROMYCIN A)
Affinity DataIC50: 88nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  94nMAssay Description:Binding affinity to human IARS incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50222902BDBM50222902(CHEMBL1163069)
Affinity DataIC50: 98nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075063BDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217935BDBM50217935(CHEMBL114859)
Affinity DataIC50: 100nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075068BDBM50075068(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50290689BDBM50290689(9-{(E)-4-[(2S,3R,4R,5S)-5-(3-Chloro-propane-1-sulf...)
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50075065BDBM50075065(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075062BDBM50075062(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Escherichia coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217844BDBM50217844(CHEMBL115953)
Affinity DataIC50: 168nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075063BDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 200nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075062BDBM50075062(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 240nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50290687BDBM50290687(9-{(E)-4-[(2S,3R,4R,5S)-5-(Butane-1-sulfonylamino)...)
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50290688BDBM50290688(9-{(E)-4-[(2S,3R,4R,5S)-5-(3-Chloro-benzenesulfony...)
Affinity DataIC50: 300nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50075059BDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 300nMAssay Description:Compound tested for the inhibition of Staphylococcus aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479282BDBM50479282(CHEMBL505238)
Affinity DataIC50: 312nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075068BDBM50075068(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)
Affinity DataIC50: 330nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075070BDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 370nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075061BDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 400nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479276BDBM50479276(CHEMBL461144)
Affinity DataIC50: 433nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217849BDBM50217849(CHEMBL115317)
Affinity DataIC50: 554nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479275BDBM50479275(5-EPIREVEROMYCIN A)
Affinity DataIC50: 572nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217839BDBM50217839(CHEMBL327131)
Affinity DataIC50: 801nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479273BDBM50479273(CHEMBL498825)
Affinity DataIC50: 995nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50075065BDBM50075065(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50: 1.02E+3nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50366874BDBM50366874(CHEMBL605809)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479280BDBM50479280(SPIROFUNGIN A)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479272BDBM50479272(CHEMBL455272)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217937BDBM50217937(CHEMBL114949)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479279BDBM50479279(CHEMBL510665)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217842BDBM50217842(REVEROMYCIN B)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479270BDBM50479270(CHEMBL499655)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479283BDBM50479283(CHEMBL508146)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479269BDBM50479269(CHEMBL471857)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479271BDBM50479271(CHEMBL515541)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50479268BDBM50479268(SPIROFUNGIN B)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 84 total ) | Next | Last >>
Jump to: